Plasma Levels of Pentraxin-3, an Inflammatory Protein Involved in 1 Fertility, Are Reduced in Women with Polycystic Ovary Syndrome

1 Flavia Tosi, MD, 1 Daniela Di Sarra, MD, 2 Cecilia Bonin, MD, 1 Francesca Zambotti, MD, 1 Marlene 4 Dall’Alda, MD, Tom Fiers, MD, Jean-Marc Kaufman, MD, Matilde Donati, MD, Massimo Franchi, MD, 5 Maria Elisabetta Zanolin, MSc, Enzo Bonora, MD, Paolo Moghetti, MD. 6 7 Endocrinology, Diabetes and Metabolism, and Obstetrics and Gynecology, University of Verona and 8 Azienda Ospedaliera Universitaria Integrata Verona, I-37126 Verona, Italy; Laboratory for Hormonology, 9 and 4 Department of Endocrinology, Ghent University Hospital, B-9000 Ghent, Belgium; 5 Department of 10 Public Health and Community Medicine, University of Verona, I-37131 Verona, Italy. 11 12 13 Corresponding author: Prof. Paolo Moghetti 14 Address: Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of 15 Verona, P.le Stefani, 1 I-37126 Verona, Italy 16 e-mail: [email protected] 17 Telephone number: +39.045.812.3110; Fax number: +39.045.802.7314 18 19 Running title: Pentraxin-3 in PCOS women 20